Cycloartane glycosides from the rhizomes of Cimicifuga racemosa and their cytotoxic activities.

نویسندگان

  • Kazuki Watanabe
  • Yoshihiro Mimaki
  • Hiroshi Sakagami
  • Yutaka Sashida
چکیده

Phytochemical analysis of the rhizomes of Cimicifuga racemosa (Ranunculaceae) resulted in the isolation of twelve cycloartane glycosides (1--12), including four new ones (4--6, 12). The structures of the new compounds were determined by spectroscopic analysis, including two-dimensional (2D) NMR data, and chemical methods. The isolated compounds were evaluated for their cytotoxic activities against human oral squamous cell carcinoma (HSC-2) cells and normal human gingival fibroblasts (HGF).

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عنوان ژورنال:
  • Chemical & pharmaceutical bulletin

دوره 50 1  شماره 

صفحات  -

تاریخ انتشار 2002